Abstract
Probiotic products are currently often encountered in our daily life as well as the term “Probotics”. The prevalence of probiotic products is not confined to Japan but extends throughout the world due to individuals’ interest in health based on scientific information. At this point, I would like to look back at the historical background behind the prevalence and globalization of probiotic products, including their concept and the alteration of the definition of probiotics, and think about the scientific aspects of probiotics on the way to biomedical development, starting from the improvement of intestinal disorders by feeding fermented milk and yogurt or bacterial preparation as supplements. Finally, I would like to consider the future of probiotics in relation to the regulation of health claims about probiotic products, which will affect the direction of development of probiotics.
