Abstract
Eight healthy volunteers, 5 females and 3 males, ranging from 21 to 50yr (average 28yr) participated in this study. Yoghurt (130g) prepared with Lactobacillus delbrueckii subsp. bulgaricus strain 2038 and Streptococcus salivarius subsp. thermophilus strain 1131 was administrated, three times a day for 2 weeks. The numbers of bifidobacteria in feces of all subjects were increased and then the viable counts of Clostridium (lecithinase negative) were significantly decreased, respectively, by the administration of yoghurt. In addition, the concentration of the fecal-putrefactive metabolites such as p-cresol and indole were also decreased by the administration of yoghurt. The decrease in fecal pH was also found by the administration of yoghurt.