Abstract
A case of intraductal papilloma of the breast showing an unusual pattern of calcification on mammography is reported. A 26-year-old woman noticed a right breast mass in the CD area with white nipple discharge and visited our hospital. Nipple discharge cytology was negative. Mammography showed amorphous microcalcifications in a clustered pattern that reflected terminal duct lobular units. Duct ectasia and an intracystic papillary lesion in the CD area were revealed by ultrasonography, and persistent enhancement was revealed by magnetic resonance imaging (MRI). A duct-lobular segmentectomy was therefore performed under a radiological diagnosis of intraductal papilloma. Histologically, the surgically resected lesion was an intraductal papilloma with focal prominent sclerosis, in which numerous microcalcifications were embedded. The calcification was considered to have been derived from condensed secretory material in the small ductules within the papilloma. The walls of the original ductules seemed to be obscured by prominent sclerosis, leaving only calcified material in the sclerosed stroma. The possibility that papilloma may show an unusual pattern of calcification should be borne in mind.
