Abstract
The majority of abnormal findings of screening mammography are microcalcifications with no clinical symptoms. Here we present a case of DCIS that showed rapid progression of microcalcifications on screening mammography.
A５５―year―old woman was recalled for further examination of pleomorphic, widely extended and segmental microcalcifications in region C of the right breast. Ultrasound showed an extended low―echoic area with some high―echoic spots in the same area. Mammography in the previous year had also indicated small microcalcifications. A core needle biopsy revealed ductal breast cancer. The patient underwent total mastectomy with the nipple and areola complex of the right breast due to spread of the microcalcifications to the nipple. Sentinel axillary node biopsy confirmed no metastasis. Pathology of the surgical specimen revealed extended DCIS（comedo type）, with a profile of ER（―）, PgR（―）, HER２（３＋）, Ki―６７（＞３０％）and Nuclear grade ３. Mammoplasty of the right breast is scheduled.
It is important to detect high―risk DCIS in screening mammography.
