Abstract
Analyzing crystal growth mechanism of molecular assembly in cells in concern with the corresponding physiological activity will be useful for the study of cell biology. The morphology of microtubules in human lymphoblast was observed at high pressure. The pressure-induced denaturation of α-tubulin was observed at a pressure of 100MPa, which melted the microtubulus. The possibility of microtubules participating in the molecular mechanism of apoptosis was pointed out for the first time.
