Abstract
54-year old male was admitted in the Emergency Department at our hospital with a complaint of melena, and rectal cancer was diagnosed on thorough examination. He had suffered a stroke 2 months ago, and then regularly attended to Neurology Department for further investigation and treatment until before the onset of melena. Preoperative CT and PET-CT showed no distant metastasis, and low anterior resection was performed. During the operation, multiple metastatic nodules were observed all over the liver. Pathological diagnosis indicated adeno-endocrine cell carcinoma. After the operation, bleeding gastric ulcer led him into shock. Endoscopic banding and massive transfusion were performed, but his liver gradually went into failure. One month after the operation, he was treated 3 cycles of mFOLFOX6 and associated with such complications as acute cholecystitis. Three months after the operation, he died of liver and renal failure. In this case, we chose the treatment of mFOLFOX6 for colorectal cancer, but treatment for small cell lung cancer is also suggested according to NCCN guideline. The establishment of treatment for adeno-endocrine cell carcinoma is expected in Japan.
