Abstract
We report a case with the episode of suspected pneumocystis pneumonia(PCP) during chemotherapy for gastric cancer. A sixty-year-old man with clinical Stage Ⅳ gastric cancer was treated with chemotherapy by S-1 plus CDDP, PTX and S-1 plus TXT. During washout period, he was admitted for respiratory distress. He was diagnosed PCP from bilateral diffuse ground glass opacities of X-ray and computed tomography (CT), in addition to the elevated serum β-D-glucan. Following treatment of trimethoprim-sulfamethoxazole and corticosteroids with ventilator management, his clinical condition and his chest imaging findings were improved. PCP is known as a potentially fatal opportunistic infection and develops generally in patients undergoing immunosuppressive therapy or Human immunodeficiency virus infection. It requires close attention to PCP during chemotherapy and corticosteroid treatment for gastrointestinal cancer patients.
