Abstract
A 42-year-old woman, who was found to have a submucosal tumor (SMT) of the stomach in medical check up, was transfered to our hospital with a diagnosis of gastrointestinal stromal tumor (GIST) suspected from community hospital. Upper gastrointestinal endoscopy revealed intraluminal growth type SMT with 20mm in size at the greater curvature of the middle body of the stomach. CT scan demonstrated well enhanced intraluminal type SMT at the middle body of the stomach. The enhancement pattern was very similar to that of hemangioma. Subsequently, she received laparoscopic and endoscopic cooperative surgery with a diagnosis of SMT of the stomach highly suspicious of GIST. Pathological examination demonstrated that the tumor was composed of solid sheets of polygonal small cells around well-developed capillary vasculature. Immunohistochemistry revealed strong expression of α-SMA and collagen-Ⅳ and no expression of KIT, CD34, desmin or S100. MIB1 index was very low (1-2%). The tumor was finally diagnosed as benign glomus tumor of the stomach. Postoperative course was uneventful and she discharged hospital 6 days after operation. She is free of recurrence at 1 year after operation.
