Abstract
A 64-year-old women admitted to a nearby hospital because of abdominal pain, diarrhea and thirst. On laboratory testing, increased serum pancreatic enzymes and HbA1c, she was referred to our hospital on suspicion of chronic pancreatitis. An abdominal enhanced CT showed a mass measuring 25mm in diameter located in the head of the pancreas, and pancreatic cancer was suspected. Endoscopic ultrasound guided fine needle aspiration biopsy (EUS-FNAB) was done from the mass of pancreas, cytological diagnosis of anaplastic carcinoma with osteoclast-like giant cell type of the pancreas. After careful examination, she was diagnosed synchronous triple cancer including right breast cancer and papillary thyroid cancer. Progression of right breast cancer and papillary thyroid cancer is slowly, pancreatic cancer is determined to be prognostic factor. She underwent subtotal stomach preserving pancreaticoduodenectomy. Anaplastic pancreatic carcinoma is rare and is associated with poor prognosis. Synchronous triple cancer including anaplastic carcinoma is very rare, and only 1 cases, have been reportes in Japan. We reported this patient and review the literature.
