Abstract
A 64 year old man was taken to an emergency room in our hospital with syncope and melena in August, 2012. An urgent upper gastrointestinal endoscopy was done. Submucosal tumor with ulceration and blood clot existed in middle part of the stomach accompanied with an early gastric cancer near it. Another submucosal tumor was represented in upper site of the stomach. We have diagnosed simultaneous existence of gastrointestinal stromal tumor (GIST) and early gastric cancer. Total gastrectomy with lymphadenectomy and resection of the spleen were performed. Histopathological and immunohistochemical study showed the both of submucosal tumors were GIST, which indicated positive for KIT and CD34. Histology of the early gastric cancer was poorly differentiated adenocarcinoma. The patientʼs postoperative course was doing well, then he was discharged from the hospital on the 17th postoperative day. Coexistence of GIST and gastric cancer represents about 0.29 percent of resected gastric cancer, and only 29 cases have been reported in the Japanese literature. We report this case here because simultaneous existence of GIST and gastric cancer with pre-shock onset due to gastrointestinal hemorrhage is uncommon.
