Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons)
Online ISSN : 1882-9112
Print ISSN : 0385-7883
ISSN-L : 0385-7883
CASE REPORTS
A Case of Curative Surgical Resection of Gastric Gastro Intestinal Stromal Tumor After Neoadjuvant Chemotherapy with Imatinib
Hirokazu Kubo, Takashi Oshima, Chikara Kunisaki, Mitsuyoshi Ota, Tadao Fukushima, Itaru Endo
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2015 Volume 40 Issue 4 Pages 705-711

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Abstract
A 66-year-old man presented with abdominal distention. Abdominal computed tomography (CT) showed a huge tumor 25cm in diameter that was suspected to directly invade the transverse colon and the pancreas. The patient was given neoadjuvant chemotherapy with imatinib (400mg/day) to reduce the risk of surgery and to promote functional preservation. After 24 weeks of treatment, CT revealed massive degeneration of the tumor. Sleeve resection of the stomach with partial resection of transverse colon was performed. The tumor invaded only the transverse mesocolon, and curative resection was possible without rupture. The patient postoperatively received adjuvant chemotherapy with imatinib, and there has been no evidence of recurrence as of 18 months after surgery.
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© 2015 Japanese College of Surgeons
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