2016 Volume 41 Issue 5 Pages 738-742
We analyzed the clinicopathological characteristics, pre- and intraoperative diagnoses, surgical operations, chemotherapies, and prognoses of 13 patients with primary appendiceal carcinoma resected in our hospital between January 1990 and December 2013. The patients (6 males, 7 females) were aged from 56 to 94 years old (mean: 73.4 years old). We could diagnose only one patient pathologically before surgery, 6 patients intraoperatively, and 6 patients after surgery. We performed right hemicolectomy in 5, ileocecal resection in 6, partial resection of the cecum in 1, and appendectomy in 1. The histological type was well-differentiated adenocarcinoma in 9, moderately differentiated adenocarcinoma in 3, and papillary adenocarcinoma in 1. The tumor depth was T2 in 1, T3 in 5, and T4 in 7. The pathological stage was stage Ⅱ in 6, Ⅲa in 4, Ⅲb in 1, and Ⅳ in 2. The postoperative median follow-up duration was 43 months (2-169). Regarding the prognosis, 5 patients remained alive without recurrence, 3 died of other diseases without recurrence, 3 died of peritoneal dissemination, 1 died of liver metastasis, and 1 died of recurrence involving the appendiceal stump. The overall 5-year survival rate was 51.9%. The clinical stage is usually advanced at the time of surgery. Primary appendiceal carcinoma may have a tendency to recur through peritoneal dissemination, and so postoperative chemotherapy may be more important.
