Thirteen Cases of Primary Appendiceal Carcinoma

Abstract

Appendiceal carcinoma is relatively rare. Between July 2011 and December 2016, we encountered 13 cases of primary appendiceal carcinoma in our hospital. We analyzed the clinical and pathological characteristics, operations, and outcomes of the cases. The median age (range) was 63 years (36-85). The operations were right hemicolectomy (n=1) and ileocecal resection (n=12). Tumor depths were T1 (n=1), T2 (n=1), T3 (n=1) and T4 (n=10). Histological types were moderately differentiated adenocarcinoma (tub2; n=2), poorly differentiated adenocarcinoma, solid type (por1; n=1), and mucinous adenocarcinoma (muc; n=10). Pathological stages were Ⅰ (n=2), Ⅱ (n=6), Ⅲb (n=1), and Ⅳ(n=4). The postoperative median (range) follow-up duration was 37 months (4-60). Regarding outcomes, 10 cases remain alive without a recurrence, but 3 cases died, 2 from a recurrence. Preoperative diagnosis of a primary appendiceal adenocarcinoma is difficult, and the clinical stage is usually advanced when the diagnosis is made. Further cases are necessary to clarify the standard therapy.