Abstract
High performance biomaterials have been expected to play a substantial role in near future-directed cardiovascular medicine. Man-made or hybridized biomaterials serve to impart biocompatibility and functions to advanced artificial organs. In this paper, more than several years-efforts of biomaterial research in the Artificial Heart Group at the National Cardiovascular Center was summarized. These include ventricular assist device, surgical adhesive, anaphylatoxin scavenging device, hybrid artificial graft based on organ reconstruction technology.