Abstract
In this study, we examined the strength and persistence of the antibacterial effect of polycarboxylate cement(PC) combined with Tannin-Fluoride preparation(HY-agent, HY-PC)on oral bacteria(19 strains of 19 species)containing cariogenic and periodontal bacteria. The HY-PC showed the antibacterial effect on all bacteria tested. The effect differed by species. In addition, the HY-PC also inhibited the growth of bacteria in saliva and dental plaque. Although the antibacterial effect of HY-PC was significantly decreased by immersion in saline for 1 day, decrease of the effect was not observed in immersion for 2 to 7 days, implying that the significant effect remained even after immersion for 7 days. These results suggest that HY-PC with wide range of antibacterial spectra is useful for killing bacteria in the oral cavity and would facilitate the control and prevention of caries recurrence.