Abstract
A 75-year-old man undergoing gastrointestinal endoscopy for examination of a gastric ulcer and found to have a reddish region at the esophagogastric junction (EGJ). This biopsy was found to have adenocarcinoma of the abdominal esophagus necessitating lower esophagectomy through a left thoracoabdominal approach and proximal gastrectomy. Histological examination showed specimens to be revealed well differentiated tubular adenocarcinoma, involving the submucosal layer, but no metastasis to lymph nodes. In this case, No Barrett esophagus or ectopic gastric mucosa were seen around the tumor and most tumor cells were located in the esophageal lamina propia, rather than in the submucosal layer, suggesting that the tumor originated from the cardiac glands of the esophagus.