Abstract
A 59-year-old man underwent radical right nephrectomy for renal cell carcinoma (RCC) in December 2008. Two years later, a follow-up CT showed two lung metastases and gallbladder (GB) tumor, and he was treated with IFN-alpha. While lung metastases kept the disease stable, the GB tumor was progressively growing. He developed acute cholecystitis in November 2011. Abdominal enhanced CT showed a 35 mm GB tumor which was enhanced well at early-phase and washed out at delayed-phase. We suspected the GB tumor of metastasis from RCC. Because of the stable condition of lung metastases and treatment of cholecystitis, we selected a surgical approach for GB tumor. We performed extended cholecystectomy. Macroscopic appearance of the resected GB revealed a 6 cm nodular type soft tumor. Histopathologically, the tumor indicated clear cell carcinoma and was diagnosed as metachronous GB metastasis. Furthermore, blood clotting attached to the surface of the tumor and the GB was filled with hemobilia, so we suspected tumor hemorrhage. RCC is commonly known as metastasizing various organs including GB. So far, there are only 48 cases of GB metastasis from RCC.
