A Case of True Carcinosarcoma Arising from the Left Hepatic Duct

Abstract

A 75-year-old man was referred to our hospital with a diagnosis of left hepatic duct carcinoma. The abdominal CT scan revealed thickened bile duct wall of the left and common hepatic ducts and dilated intrahepatic bile ducts of the left liver. Endoscopic retrograde cholangiography showed a filling defect at the hepatic duct confluence. We performed left hepatectomy with caudate lobectomy and extrahepatic bile duct resection. Macroscopic examination showed a papillary tumor originating from the left hepatic duct. Histologically, the tumor consisted of a mixture of ‍adenocarcinoma with a squamous cell carcinoma component and spindle-shaped sarcomatous cells with osteogenesis. Immunohistochemically, the sarcomatous element was negative for AE1/AE3 and positive for vimentin, resulting in a diagnosis of in true carcinosarcoma.