Abstract
An 84-year-old man presented with anorexia and epigastric pain. Endoscopic examination revealed a type 3 tumor of the entire circumference of the antrum. The pathological diagnosis of a biopsy specimen was squamous cell carcinoma. Thoracoabdominal pelvic contrast CT revealed no distant metastasis. Squamous cell carcinoma or adenosquamous carcinoma was diagnosed and distal gastrectomy with Roux-en-Y anastomosis, D2 lymph node dissection, omentectomy, and cholecystectomy were performed. The histological diagnosis of the resected tumor was pure squamous cell carcinoma without an adenocarcinomatous component, of which most carcinoma cells were immunoreactive to p40 antibody. The pathological findings were as follows: pT3 (SS), int, INFb, ly0, v2, pN0, M0, P0, CY0, H0, and Stage IIA. Primary gastric squamous cell carcinoma is considered very rare and the incidence of this histological type is approximately 0.09%. Here we report a rare case of primary gastric squamous cell carcinoma diagnosed by immunohistochemical analysis of p40.
