2017 Volume 50 Issue 1 Pages 9-17
A 69-year-old woman was admitted to our department because of a liver tumor. CT angiography revealed a single liver tumor at the S6 region 35 mm in diameter. The tumor was stained in the arterial phase but was not stained in the portal phase. The patient was given a diagnosis of metachronous liver metastasis from rectal cancer due to imaging findings and history of rectal cancer. Laparoscopic partial liver resection of S6 was performed. Immunohistochemically, the tumor cells were positive for synaptophysin, chromogranin A and CD56. MIB-1 labeling index was over 90 percent. The final diagnosis was primary hepatic neuroendocrine carcinoma. The patient suffered from lung and remnant liver recurrence during the early postoperative period. In spite of sequential chemotherapy, she died 19 months after surgery. Primary hepatic neuroendocrine carcinoma is extremely rare, and has a poor prognosis.
