2018 Volume 51 Issue 3 Pages 245-252
Clinical course and prognosis of 17 patients aged under 30 years old with abdominoperineal resection (APR) for severe anorectal Crohn disease were reported. Anorectal complications were anorectal stenosis (n=12), complex perianal fistula (n=9), rectal fistula (n=4), rectovaginal fistula (n=2), pelvic abscess (n=2), rectourethral fistula (n=1), perirectal abscess (n=1), aggressive ulceration (n=1), anal fistulous cancer (n=1). These complications had a deleterious effect on daily life and restricted social activity of all patients. Following APR, their symptoms caused by anorectal Crohn disease were improved and 15 patients (88%) had work or went to school. Post-operative complications occurred in 14 patients (82%), such as stoma-related complications (n=8), surgical site infection (n=5), delayed perineal wound healing (n=3), sexual dysfunction (n=2), adhesive intestinal obstruction (n=2). APR for severe anorectal Crohn disease is effective in terms of improving the symptoms and offering relatively good social life, irrespective of some post-operative complication. APR should be considered for severe anorectal Crohn disease, even in younger patients.