2023 Volume 56 Issue 1 Pages 1-9
A 72-year-old woman had undergone left mastectomy for invasive lobular carcinoma 6 years ago. She developed jaundice during follow-up, and abdominal enhanced CT revealed a 19-mm mass in the duodenal papilla. Histopathological examination of endoscopic ultrasound-guided fine-needle aspiration biopsy revealed atypical cells, which led to diagnosis of primary duodenal papillary cancer. Subtotal stomach-preserving pancreaticoduodenectomy was performed. Histopathological examination revealed a well-defined nodular lesion in the duodenal papilla that exhibited the pathological features of primary breast cancer. An immunohistopathological examination confirmed metastasis of breast cancer to the duodenal papilla. During postoperative follow-up, uterine metastasis was detected and systemic chemotherapy was administered. However, peritoneal disseminated metastases and brain metastasis were subsequently detected, and the patient died 11 months after the pancreatic surgery. Gastrointestinal metastasis of breast cancer has been reported in several cases, but duodenal papilla metastasis is extremely rare. Here, we report a case of resection of duodenal papilla metastasis that developed with obstructive jaundice 6 years after surgery for breast cancer.
