Characteristics of Clinico-Pathological Findings in Pre and Post Menopausal Female Gastric Cancer

Abstract

This study was designed to investigate the relationship between gastric cancer in women and their endocrine environment. We compared 24 premenopausal female patients (20-39 y.o) with 152 postmenopausal patients (60-79y.o) with gastric cancer clinicopathologically. We also investigated the estrogen receptor positive rate in those patients. Gastric cancer in the premenopausal patients tended to be of the poorly differentiated type and scirrhous type more often than in the postmenopausal patients. The destrogen receptor positive rate in the premenopausal patients was 100% and tended to decrease with age. Our data suggest that gastric cancer in women are influenced by their endocrine status.