Abstract
The distance of discrepancy (DD) between macroscopic and histological measurement of the oral margin ingastric cancer was clinico-pathologicallly examined. The subjects were 248 patients with advanced gastric cancer, on whom a curative operation had been performed more than 5 years earlier. The DDs of these cases were comparedaccording to depth, histological type and macroscopic type of the main lesion. The results showed that misdiagnosiswas mostly related to the macroscopic type, and the DD of the infiltrative type was statistically larger than that ofthe localized type in underestimated cases (p<0.05). As for background, the ratesof stage 3, scirrhous growthpattern and INFγ were higher in the infiltrative type, whereas no difference was seen in the factors of lymphaticpermeation, venous invasion and tumor size. In contrast with a DD of less than 9mm in 93.3% of the cases of thelocalized type, a DD of 19 mm was required for the infiltrative typeto attain the same rate. In conclusion, more careshould be taken about the cutting line of gastrectomy in the infiltrative type of cancer.
