Abstract
We report a rare case of a lymphoepithelial cyst (LEC) of the pancreas associated with pancreatic carcinoma. A 58-year-old man reporting abdominal pain and found to have a cystic mass in the pancreatic tail, and high serum CA19-9 was found in computer tomography and angiography to have a possible cystic neoplasm of the pancreas, possibly a cystoadenocarcinoma. Subsequent distal pancreatectomy diagnosed the mass as LEC. One year later, his serum CA19-9 again was elevated, and a solid cystic lesion was found in the residual pan-creas. Endoscopic fine-needle aspiration biopsy showed cancer in the residual pancreas, necessitating total pancreatectomy. LEC is a rare benign cyst of the pancreas lined by squamous epithelium and uncertain of pathogenesis. To our knowledge, this is the first report of LEC of the pancreas associated with pancreatic can-cer.