¹³⁷Cs内部照射が雄生殖器に与える影響についての実験的研究

第2編 ¹³⁷Cs内部照射を受けたハツカネズミ睾丸の組織変化の経時的追求と¹³⁷Csの体内分布について

抄録

The distribution of ¹³⁷Cs in mice body and changes of germinal cells in seminiferous tubuli following ¹³⁷Cs administration.
Hundred and twenty male mice were given 8μc of Cs per gram of body weight (the first group) or 4μc Cs per gram of body weight (the second group) intraperitoneally. Animals were sacrificed at 1, 3, 10, 20, 30, 40, 50, 60, 70, 80, 90 and 100 days after the injection. Testis of right side, kidney, spleen, liver, heart and lung were extirpated and measured the radioactivity. Histological preparations were made from testis of left side.
The results are as follows:
1) In the testis, the radioactivity reached the 3rd day after the injection, and then decreased gradually along the time elapsed untill 100 days. But its activity was always higher than any other organs except 24hrs after the injection.
2) The order of the radioactivity in each organ was: heart>kidney>liver>spleen>lung.
3) Degeneration and decrease in number of spermatogonia were found already 10 days after the injection. These changes were measured by the method described by Wattenvyl.
4) Thirty days after the treatment, injurise were the most.
5) Recovery was observed from 30 days and reached 90 percent on 70 days after the injection.
6) In these histological changes, the first group showed more marked injurious changes compared with the second group.