Abstract
Daily cobalt chloride injection for three days produced a rise of basal blood glucose concentration accompanied by the elevation of basal insulin levels as well as glucose-stimulated insulin secretion in rabbits, while the sum of blood glucose concentration following oral glucose remained normal. Hypertriglyceridemia observed in cobalt-treated rabbits correlated highly with glucose-stimulated insulin secretion. Higher concentration of plasma FFA was observed in pair-fed control rabbits as comparedto the cobalt-treated rabbits.
