1988 Volume 43 Issue 3 Pages 736-740
The effects of vitamin C intake on percentages of LDH-4 and LDH-5 fractions were examined in 5 healthy volunteers. The experiment lasted 43 months (usual diets; 12 months, usual diets+vitamin C 1g/day; 24 months, usual diets; 7 months). The variations of the percentages of LDH-4 and LDH-5 fractions were measuerd.
The results obtained were as follows.:
The percentage of LDH-4 in all subjects decreased with vitamin C adminstration, and decreased significantly (p<0.05) from 8.3±0.98% to 6.9±0.75% after 24 months.
The percentage of LDH-5 in all subjects decreased after vitamin C administration, and decreased significantly (p<0.05) from 9.4±4.9% to 8.0±3.95% after 24 months.
It is possible to conclude from the results that the percentages of the LDH-4 and LDH-5 fractions were affected by long-term vitamin C loading.