Abstract
Nuclear DNA was measured by microphotometry in 15 cases of thyroid cancer. Samples were prepared from paraffin embedding material, and DAPI-staining was performed. The comparative review was made with follicular carcinoma and papillary carcinoma as studied previously. There was no particular relation between the proliferative index (PI) and existence of vascular or capsular infiltration. The irregularity of the nucleus and fine needle aspiration (FNA) before surgery were related to the proliferative index.
The metastasis of lymph node showed a aneuploidal tendency.
The PI-value was 14.2±7.9 on follicular carcinoma, 5.0±3.3 on adenoma, and 16.0±6.4 on papillary carcinoma. The value with follicular carcinoma was low, because it might be due to the inclusion of 6 cases of follicular carcinoma with minimal invasion.
