Abstract
Over a peried of 15 years, the authors treated with intraarterial injection therapy for 22 cases of other than cancer of the nose and paranasal sinuses occurring on the head and neck. The following results were obtained.
(1) The patients, in which 11 cases of oral cancer and 8 cases of oropharyngeal cancer, etc., predominantly male, ranged in age from 38 to 82 years.
(2) Thirteen of the 22 patients were treated with a cisplatin combination therapy and 12 cases were treated with neo-adjuvant chemotherapy.
(3) At the time of 60th month, the accumulated survival rate as judged by the Kaplan-Meier method of 55% and 86% for oral cancer and oropharyngeal cancer, respectively, was found.
(4) At the same period, this rate of 85% and 26% for cisplatin combination therapy and other drugs therapy, respectively, was found.
(5) This rate among the 12 neo-adjuvant chemotherapy was 92% at the time of 56th month.
(6) It is suggested that neo-adjuvant chemotherapy combined with cisplatin should be the therapy of choice for head and neck cancer.