Abstract
Having scheduled to perform a sagittal split ramus osteotomy on a 26 year old female patient, upon pre-operative examination, no abnormal conditions were seen in blood count and biochemical laboratory tests, but, although PT was normal, APTT alone was prolonged to 43.2 seconds for blood coagulation tests.
Surgery was postponed, and upon detailedexamination, a decline in Factor XII to 30% was observed and diagnosedas a heterozygotic depletion of Factor XII. Having decided that possibility of bleeding tendencies were clinically low, surgery was performed without supplementation of coagulation factors.
Bleeding during surgery was 150ml, and fluid from the post-operative drainage placed in the wound was 65 ml for 2 days, showing no particular tendencies of hemorrhage. Nonetheless, since there still were possibilities that hypercoagulation could occur, careful observation was considered necessary.
