A case of wisdom tooth extraction using platelet-rich plasma (PRP) and application of atelocollagen sponge to the site of extraction in a patient with myelodysplastic syndrome

Abstract

The myelodysplastic syndrome (MDS) is characterized by pancytopenia, not only a decrease in the number of blood cells but also the morphological and functional abnormalities.
A 28-year-old female with this syndrome was referred to our clinic. We extracted the horizontally impacted left lower wisdom tooth after transfusion of platelet concentrates. The amount of transfusion was half compared with the previous extraction of the half erupted right lower wisdom tooth. Attelocollagen sponge soaked with platelet-rich plasma (PRP) was inserted into the site of extraction followed by the closure of the envelope flap.
Excellent healing process was obtained at the site of extraction of the left lower wisdom tooth in comparison with the previously extracted right wisdom tooth one month earlier. Radiopacity and soft tissue healing was clinically similar.
The therapeutic improvements achieved by using PRP with atelocollagen sponge has demonstrated the possibility of decreasing the amount of platelet infusion and avoidance and/or prevention of hemorrhagic complications. In consequence, this method has revealed its handiness, its safeness and above all the reduction in time requirement for wound healing as compared with a simple platelet transfusion.