水―パーフルオロカーボン系の水平管内二相流の層状流形成

抄録

Stratified flow in liquid-liquid two-phase flow of water-perfluorocarbon（PFC）system is expected to be utilized in biomedical engineering. In particular, the stratified flow is considered to be used for the research of cell sorting and transporting method for cell treatment process of transplantation. This method can transport cells without any damages and supply oxygen to cells. However, studies on liquid-liquid two-phase flows have been conducted mainly in oil-water systems, and there have been few studies under the condition where water is the upper layer. There is also little research on the shape of the interface for stratified flow, which is required for living cells sorting. In this study, we investigated the conditions for the formation of stratified flow in a water-PFC system using experimental and numerical simulation. The volume of fluid (VOF) method was employed to predict the interface shape of the stratified flow depending on the Weber number and the Eötvös number. As a result, the formation of stratified flow was observed in the range of We≥1 and in the range of We≥0.05 and Eo≥4. From the analysis, no significant difference in the interface shape was observed in this experimental condition range. Therefore, we can employ this flow system for cell treatment process to develop novel devices for cell therapy.