2019 Volume 39 Issue 1 Pages 20-23
Deformable image registration (DIR) can be used for accurate dose mapping between multiple radiotherapy image set. Dose accumulation based on DIR is playing an important role in advanced radiation therapy, such as 4 dimensional radiation therapy and adaptive Radiotherapy. The accuracy of dose mapping depends on the accuracy of the deformation vector fields arising from DIR and on the local dose gradient in the irradiated geometry. Therefore, in clinical use, patient-specific verification should be performed. In this article, challenges and points to notice on DIR based dose accumulation are overviewed and discussed briefly.