2021 年 41 巻 2 号 p. 38-41
In this study, we evaluated the association between time-dependent apparent diffusion coefficient (ADC) at different diffusion times and histopathological features, such as the cellular area in a tumor and Ki-67 labeling index, in two breast cancer xenograft models. The ADC values decreased with diffusion time (from 2 ms to 27.6 ms). ADC change can be a more useful quantitative parameter than single ADC measures for estimating detailed pathological features, and it might also reflect tumor proliferation.
