Abstract
We report an unusual case of actinomycotic osteomyelitis with bone destruction. A 65-year-old man presented with swelling and induration on the right side of the mandible. Radiographic examination revealed bone destruction in a symphyseal lesion of the mandible. On the basis of these findings, the lesion was clinically diagnosed as osteomyelitis or a neoplasm of the mandible. Histopathological studies showed the presence of sulfur granules of the Actinomyces and granulation tissue. These findings led to the final diagnosis of actinomycotic osteomyelitis of the mandible. Surgical curettage was performed, together with the prolonged administration of antibiotics. Three months postoperatively, accumulation of 99mTc-MDP in the mandible had decreased, and computed tomography showed new bone formation at the lesion. There has been no relapse of disease during 1 year of follow-up.
