2018 Volume 64 Issue 12 Pages 708-714
Ghost cell odontogenic carcinoma (GCOC), a malignant counterpart of calcifying odontogenic cyst (COC) and dentinogenic ghost cell tumor (DGCT), is extremely rare. We report the case of a large GCOC arising in the mandible. A 50-year-old woman was referred to our hospital because of swelling of the left side of the mandible. Biopsy yielded a diagnosis of odontogenic carcinoma. Imaging findings revealed an extensive radiolucent lesion causing bony destruction of the mandible. In December 2014, we performed bilateral neck dissections and a segmental mandibulectomy with metal plate reconstruction using a fibula osteoseptocutaneous flap. Histopathologically, the lesion was diagnosed as GCOC because it consisted of malignant epithelial tumor and benign features of COC or DGCT. After operation, there has been no sign of recurrence or metastasis for 2 years 6 months.
