Abstract
The effect and safety of TL-102M (adhesive powder preparation containing beclomethasone dipropionate) was compared and examined in patients with multiple aphthae from 6 institutions using Aftach (adhesive topical preparation containing beclomethasone dipropionate) as a control. The results could be summarized as follows:
1. The degree of overall improvement more than ‘effective’ was 82.8% in TL-102M group and 89.7% in Aftach group.
2. No side effect was observed in either the TL-102M or Aftach groups.
3. The rate of overall impression more than ‘good’ by patient was 96.3% in TL-102M group and 82.8% in Aftach group. Although no significant difference was noted between the two groups, significantly fewer patients in TL-102M group complained no pain at the time of application as compared to those in Aftach group.
4. The degree of usefulness more than ‘useful’ was 96.6% in TL-102M group and 86.2% in Aftach group, both showing a higher usefulness in this type of disease.
