A case of upper labium carcinoma arising in a burn scar

Abstract

The developmet of squemous cell carcinoma in an old burn scar (burn scar carcinoma) of upper lip is reported.
Various causes of burn scar carcinoma arc discussed and the immunological factor that reported a burn scar is immunologically privileged site is considered important.
The status of cell-mediated immunity is examined in this case using lymphocyte blastoid transformation (blastogenesis) by PHA and Con-A.
General immunosuppression was also seen and it tended to be elevated by PSK administration.
The finding of general immunosuppression indused by large old burn scar is considered one of the factor of burn scar carcinoma.