A Clinical Study of Squamous Cell Carcinoma Related Antigen TA-4 (SSC-Ag) in Patients with Oral and Maxillofacial Lesions

Fumihiko SHINOZAKI; Kouji MATSUMURA; Tomoki MIZOBE; Teruyo FUKUDA; Masamichi IDA; Hitoshi TANABE; Yasuyuki UENO; Haruhisa IBAYASHI; Koutarou KATAYAMA; Koumei SHIGEMURA; Yoshinori HASUI; Yoshikazu HAYATSU; Kasuke NAKASHIMA

doi:10.5794/jjoms.32.2003

Fumihiko SHINOZAKI, Kouji MATSUMURA, Tomoki MIZOBE, Teruyo FUKUDA, Masamichi IDA, Hitoshi TANABE, Yasuyuki UENO, Haruhisa IBAYASHI, Koutarou KATAYAMA, Koumei SHIGEMURA, Yoshinori HASUI, Yoshikazu HAYATSU, Kasuke NAKASHIMA

Author information

Fumihiko SHINOZAKI
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Kouji MATSUMURA
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Tomoki MIZOBE
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Teruyo FUKUDA
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Masamichi IDA
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Hitoshi TANABE
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Yasuyuki UENO
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Haruhisa IBAYASHI
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Koutarou KATAYAMA
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Koumei SHIGEMURA
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Yoshinori HASUI
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Yoshikazu HAYATSU
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University
Kasuke NAKASHIMA
Department of Oral and Maxillofacial Surgery School of Medicin, Yamaguchi University

Keywords: Tumor marker, TA-4 (SCC-Ag), Oral, maxillofacial malignant tumor

JOURNAL FREE ACCESS

1986 Volume 32 Issue 11 Pages 2003-2006

DOI https://doi.org/10.5794/jjoms.32.2003

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Abstract

Squamous cell carcinoma related antigen TA-4 (SCC-Ag) was examined by radio immunoassay in 33 patients with oral and maxillofacial lesions.
In nine of 10 patients with untreated malignant tumors, there were detected high positive levels of antigen. The average data of them showed 2.97 ± 1.09 ng/ml.
After treatment, 12 patients who had no recurrences or metastasis showed relatively low positive levels, such as the average of 2.31 ± 0.83 ng/ml. However, in benign tumors, cysts and other diseases with the exception of malignant tumors, there were detected lower than standard levels (2.0 ng/ml) or TA-4.
TA-4 (SCC-Ag) appears useful for diagnosing and monitoring to learn the recurrence of metastasis of patients with oral and maxillofacial malignant tumors.

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