Abstract
A case of oral and dermis Kaposi's sarcoma was reported. A 59-year-old woman had nodules on the mouth floor, the groin surface, and median surfaces of thigh and right chest. Histopathological examination of the nodules revealed proliferation of endothelium-like cell and fibroblast-like cells with extravasation of red cells and deposition of hemosiderin in the dermis. Resected tumor tissue of oral cavity was 45mm×25mm in size. Macroscopic appearance was coarse irregular surface with several ulcerations.
Treatment with resection and immunotherapy (ok-432) in combination with chemotherapy (vinblastin, endoxan, predonine) was not effective for Kaposi's sarcoma. She died of intestinal bleeding due to thormbocytopenia and respiratory failure.