1991 Volume 37 Issue 6 Pages 1173-1176
The incidence of malignant lymphomas in head and neck region rarely occurs in the oral cavity, although it frequently develops in cervical lymphonodes or Waldeyer's ring initially. Especially tumorigenesis from the front area of the tongue is hardly reported.
A 78 year old woman was seen suffering from malignant lymphoma with the main complaint of frontal tumor of the tongue without pain. She was diagnosed as having a follicular lymphoma after surgical resection. Eleven months or later she relapsed by palpation of a supraclavicular tumor, however, the lesion disappeared by combination treatment of etoposide, cyclophosphamide and ubenimex. The possibility of metastasis may be wholly excluded, she has had good prognosis without recurrence for at least 3 years.