Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Volume 37 , Issue 6
Showing 1-19 articles out of 19 articles from the selected issue
  • Hidenori OHARA
    1991 Volume 37 Issue 6 Pages 1067-1083
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    In order to elucidate the pathogenesis of the buccal area deformity, normal development of the mouse cheek, especially the chronological changes of the area between maxillary and mandibular process (AMM) from the 9.0th day to the 14.5th day of gestation (plug day=0), was investigated by light and electron microscopy. On the 9.0-9.5th day of gestation, the first branchial arch connected directly to the fronto-nasal process and its surface epithelium was simple cuboidal and had many short microvilli. On the 10.0 th day, the maxillary process began to swell up from the first branchial arch. The epithelium between and maxillary mandibular process was flattened and its cellular margins were accentuated by the presence of numerous microvilli. There were two kinds of cells, one had numerous microvilli and the other had not. On the 10.3th day, the arrangement of the AMM cell layer was temporally random and the apoptosis was observed characteristically. After the 11.0th day, squamous peridermal cells, of which boundaries were clearly demarcated with microvilli, appeared at surface of the epithelium. Beneath the periderm, cuboidal epithelial cells arranged as one or two cell layers. After the 14.0th day, the epithelium became striated and squamous.
    Although the epithelial arrangement became temporally random at the 10.3th day, AMM epithelium existed as the compact mass and the mesenchymal cell did not migrate into the epithelium during AMM development. The phenomena which were reported to occur characteristically at the epithelial fusion during the development of the primary or secondary palate were not observed in this study.
    From these results, the development of the cheek is not from the epithelial fusion between maxillary and mandibular process but from the proliferation and the differentiation of the cells both of maxillary and mandibular process including mesenchymal cells, and the cheek develops through the relative facial development.
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  • Ken-ichi NOTANI, Hisanori MIURA, Tohru SAITO, Hiroshi FUKUDA, Masanobu ...
    1991 Volume 37 Issue 6 Pages 1084-1094
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The nuclear DNA contents of 67 oral squamous cell carcinomas were analyzed by flow cytometry and the results were compared with pathological, clinical features and clinical course.
    All benign tumors had a normal DNA content (diploid pattern) but 44.8% of sluamous cell carcinomas had an abnormal DNA content (ancuploidy pattern). It was found that aneuploidy and DNA Index (DI) were associated with a size of tumor (T), a clinical nodal involvement (N) and clinical stage but not associated with histological grade. The tumors with advanced T, N and stage tended to show an aneuploidy pattern and high DI value. The tumor with pathological nodal involvement had both a high ratio of aneuploid tumors and a high DI value. The occurrence of primary recurrence and distant metastasis might be associated with the rate of aneuploidy. Sevcnty-five percent of 12 dead patients within 3 years had aneuploid tumor (vs. 38% of alive).
    These findings suggested that flow cytometric analysis might be useful to predict the prognosis of oral s: luamous cell carcinomas.
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  • Masatoshi ISHII
    1991 Volume 37 Issue 6 Pages 1095-1113
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A genetic and epidemiological analysis was carried out on 1, 574 patients with cleft lip and/or cleft palate (CL/CP) who visited the clinic of Second Department of Oral and Maxillo-facial Surgery, Tokyo Medical and Dental University Hospital from 1960 to 1987. These patients are evaluated with respect to sex ratio, laterality, and family study. The family study includes the rate of affected families, the relationship of the type of cleft between the probands and their parents and siblings, the affected rates of the parents and siblings, the culculation of affected rates of parents and siblings of the probands in polygenic inheritance by Edwards, and the culculation of Penrose's expected relative frequency of siblings of the probands. The results of analysis above indicated that CL/CP is most likely to have the character of multifactorial inheritance.
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  • Masatoshi ISHII
    1991 Volume 37 Issue 6 Pages 1114-1121
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    152 patients with cleft lip and/or cleft palate (CL/CP) who visited the clinic of Second Department of Oral and Maxillo-facial Surgery, Tokyo Medical and Dental University Hospital were typed for HLA A, B, & C. The results of this population studies were as follows.(1) There were no antigens which showed the statistically significant association neither in male nor female patients with cleft lip alone (CL).(2) Aw 33 was significantly low only in the male patients with cleft lip and palate (CLP).(3) Aw 24 and Bw 52 were significantly high only in the male patients with cleft palate alone (CP). These results suggested that the HLAlinked susceptibility or resistant genes for CP or CLP respectively exist and that these types of clefts were different in forms of the involvement of HLA-linked genetic factors. The difference in the association of cleft with HLA between male and female might be explained by the multifactorial character of disease.
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  • Katsutoshi SUZUKI, Takakazu GOZAWA, Mitsuhiro ICHIKAWA, Kenji MOGI, No ...
    1991 Volume 37 Issue 6 Pages 1122-1128
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The lesion in 18 cases of oral lichen planus and the surrounding site about 10mm from the focus, which appeared normal as seen with the eye, were examined by the direct immunofluorescent and histopathological methods. These results were compared with 13 cases of leukoplakia examined in the same way. The results were as follows.
    1. For hyperkeratosis, degeneration of the basal layer of epithelium and a dense band of lymphocytes adjacent to the epithelium, which are thought to be very important in histopathologically diagnosing oral lichen planus, the incidence was 100%, 89% and 100%, respectively, whereas the incidence of these findings at the surrounding site of the lesion was 56%, 44% and 78%. Eleven cases (61%) including more than 2 of the above 3 findings could be seen among the 18 cases. In the leukoplakia, the incidence of hyperkeratosis, acanthosis and inflammatory cell infiltration, which are thought to be very important for the histopathological diagnosis, was lower in the surrounding site of the lesion than in the focus.
    2. In lichen planus the deposition of fibrinogen was often observed both in the focus and in the surrounding site of the lesion, and there was little difference in the localization of these sites in the complement. However, a clear difference between the focus and the surrounding site of the lesion was detected in the case of leukoplakia.
    3. These results suggest that some histopathological changes have already occurred in the surrounding site of the lesion in lichen planus, and therefore medication may be preferable to surgical therapy. On the other hand, surgical therapy is considered to be a sure method in leukoplakia.
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  • Atsushi NAKAMURA
    1991 Volume 37 Issue 6 Pages 1129-1142
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The position and size of the tongue and position of the hyoid bone in 35 mandibular prognathism patients (13 with open-bite and 22 without open-bite) were compared with those of 29 normal adults and their changes after oblique sagittal splitting osteotomy were analyzed longitudinally by cephalometric radiography with contrast media.
    Preoperatively the anteroposterior and vertical dimensions of the tongue were similar to or smaller in both patient groups than normal. The anteroposterior dimension of the tongue was within the value of 2 SDs of the mean for all patients, and the vertical dimension of the tongue was within the value of 2 SDs of the mean for all patients except one. In all of the patients, the tongues were positioned anteroinferiorly and the hyoid bones were positioned anteriorly.
    Accordingly, in most cases, the tongue was not important in the development of prognathism. Postoperatively the positions of the tongue and hyoid bone moved posteriorly and were not significantly different from their positions in normal controls.
    After mandibular setback, an amount of the setback of the tongue tip was similar to that of the mandible, and an amount of the setback of the tongue root was half of that of the mandible. The reduction of tongue length immediately after operation was attributed to this difference in setback between the tongue tip and root. The increase of tongue height resulted from the inferior shift of the valiecula and the superior shift of the tongue dorsum. However, there was a difference between the two groups in the positional change of the mandible; rotation of the mandible in the group with opne-bite was counterclockwise and it was slightly clockwise in the other group. In the group without open-bite, there was correlation between the setback of the mandible and the changes of the tongue and hyoid bone, but correlation was slight for the group with open-bite.
    In the time from immediately postoperative to one year after operation, although the mandible shifted slightly toward the preoperative position, the tongue was stable in size and maintained the position taken immediately after the operation, and the root of the tongue shifted without regard for the migration of the mandible.
    According to these results the tongue was considered to have adapted to its new environment due to changing the position of its posterior part.
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  • Kazuhiko KOSAKA, Akira YAMAGUCHI, Koichi NISHIMURA
    1991 Volume 37 Issue 6 Pages 1143-1152
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A study on the fixation effect of the Titanium bone screw with the view of examining the fixative ability of the titanium bone screw for fixing osteosynthetic mini-plate, the change in strain upon bone destraction with the depth of the screw implantation was determined by dynamic strain gauge, using pig mandibular compact bone, in experiment 1.
    In experiment 2, using canine mandibular, changes in strain upon loosening implanted titanium bone screw and stainless steel bone screw (immediately after implantation) 2 and 12 weeks after implantation were determined by the same gauge and were converted into torque.
    The following results were obtained from the comparative examina tion of both there experiments. In experiments 1, strain was increased with an increase in the depth of implantation of the titanium bone screw.
    In experiment 2, loosening torque showed almost equal values for both titanium and stainless steel immediately following implantation and decreases of almost equal values 2 weeks thereafter. 12 weeks thereafter, it showed increasing tendencies for both these metals and that to a distinctly high extent for titanium.
    The above results revealed a proportional increase in the holding ability of titanium bone screw to the depth of its implantation. In terms of the loosening torque time change, titanium showed a distinctly higher value than stainless steel 12 weeks after implantation suggesting titanium to be in state of its osseointegration. Namely, the osseointegration characteristic of titanium was suggested to increase the intraosseous fixative ability of the bone screw.
    Therefore, titanium, which has a satisfactory dynamic strength and increases holding power on the bone, was considered to be a useful bio-material.
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  • Yoshikuni FUKUYAMA, Shigetaka YANAGISAWA, Osamu SHIMIZU, Akihiro TANAB ...
    1991 Volume 37 Issue 6 Pages 1153-1158
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    We presented an outline of a surgical orthodontic correction which we performed for an acromegalic patient whose serum growth hormone (GH) was not controlled enough after removal of pituitary adenoma.
    The patient was a 35-years-old male on the first visit. Under the diagnosis of pituitary adenoma, the tumor removal was performed in September 1986. In our clinic, we performed tongue reduction on 7 June 1988 and Obwegeser-Dal Pont method on 14 March 1989, even though his serum GH was not controlled enough at that time.
    In this case there were no complications during operation and postoperative period. 21 months have passed postoperatively. There has not been a relapse, and his feature and occlusal function remain in good condition.
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  • Kenzo KIN, Shigeru UENO, Ryuichi KAJI, Moritaka SHIMA, KOZO MUSHIMOTO, ...
    1991 Volume 37 Issue 6 Pages 1159-1164
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    A case of graft-versus-host disease (GVHD) is presented. The patient was a 26 year-old female with tongue carcinoma. Blood transfusion was performed after the surgical operation.
    Although the postoperative period was uneventful, on the 10th day, severe fever, diarrhea, and whole body erythema suddenly appeared. Blood examination disclosed decrease of granulocytes and liver dysfunction. These symptoms increasingly became severe and she fell into acute dyspnca and died. Diagnosis of GVHD was made from these characteristic symptoms and skin biopsy from abdominal erythema.
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  • Yuji KAMIYA, Masahiro HINOSHITA, Shigeki OCHIAI, Masahiro UMEMURA, Hir ...
    1991 Volume 37 Issue 6 Pages 1165-1172
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The purpose of this paper is to evaluate the method of Kirschner-wire pinning for the condylar neck fracture. We recalled the patients who had accepted treatment for the mandibular neck fracture during 1982 to 1987 to our clinics. We checked 164 cases from a starting period of 6 months after initial treatment. Out of the cases we treated, 25 were treated by Kirschner-wire pinning, and of those, 19 cases were unilateral and 6 cases were bilateral.
    We evaluated these 19 unilateral cases in comparison with the 44 unilateral cases which we treated non-surgically.
    The results were as follows.
    1. Regarding morphological results, Kirschner-wire pinning group was lwtter than the non-surgical group.
    2. The Kirschner-wire pinning group showed less deviation on mouth opening compared with the non-surgical group.
    3. The functional results of Kirschner-wire pinning group were very similar with that of non-surgical group.
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  • Hiroshi NIKI, Hitoshi UCHIDA, Ichizo HOSOMI, Hakuro OKANO, Kimishige S ...
    1991 Volume 37 Issue 6 Pages 1173-1176
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
    The incidence of malignant lymphomas in head and neck region rarely occurs in the oral cavity, although it frequently develops in cervical lymphonodes or Waldeyer's ring initially. Especially tumorigenesis from the front area of the tongue is hardly reported.
    A 78 year old woman was seen suffering from malignant lymphoma with the main complaint of frontal tumor of the tongue without pain. She was diagnosed as having a follicular lymphoma after surgical resection. Eleven months or later she relapsed by palpation of a supraclavicular tumor, however, the lesion disappeared by combination treatment of etoposide, cyclophosphamide and ubenimex. The possibility of metastasis may be wholly excluded, she has had good prognosis without recurrence for at least 3 years.
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  • Tatsuo TSUJI, Yoshikazu HAYATSU, Masayasu SUETSUGU, Kanji MAEDA, Kohsu ...
    1991 Volume 37 Issue 6 Pages 1177-1178
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Koji TAKAMORI, Yoshiaki KOMIYA, Ikuhiro UCHIDA
    1991 Volume 37 Issue 6 Pages 1179-1180
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Takashi OKUDA, Tadashi YASUOKA, Hideki ICHIHARA, Tadashi OKUTOMI, Nori ...
    1991 Volume 37 Issue 6 Pages 1181-1182
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Hiroshi SUETSUGU, Kiyohito YAMAZAKI, Mitsuyoshi MATSUDA, Taiichi NISHI ...
    1991 Volume 37 Issue 6 Pages 1183-1184
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Mugio KATO, Shiro YAMADA, Atsushi SHINOHARA, Chie KATO, Noriaki KAWAI, ...
    1991 Volume 37 Issue 6 Pages 1185-1186
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Youji MIYAMOTO, Fumihiro MATSUMOTO, Yukio TAKISHITA, Masaru NAGAYAMA, ...
    1991 Volume 37 Issue 6 Pages 1187-1188
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Masayuki TAKAHASHI, Junichi TANAKA, Tamotsu KAGAYA, Hisashi SATO, Tomo ...
    1991 Volume 37 Issue 6 Pages 1189-1190
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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  • Shouko TAKETOMI, Tadao SUGIMOTO, Takashi NAKAMURA, Hiroshi IKEDA, Sato ...
    1991 Volume 37 Issue 6 Pages 1191-1192
    Published: June 20, 1991
    Released: July 25, 2011
    JOURNALS FREE ACCESS
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