Experimental study of the analgesic effect of kaikyushokushou-to (TJS-022)

Abstract

Although some doctors use kampo medicine clinically, it has not yet achieved general acceptance. This seems to be partly caused by the paucity of reports on the effects of kampo medicine as evaluated by basic research. We performed a comparative study of the analgesic effects of kaikyushokushou-to (300, 600, 1200mg/kg, per os), saline (negative control), and diclofenac sodium (poistive control) in mice. All doses of kaikyushokushou-to had an analgesic effect. These results suggest that kaikyushokushou-to can be used for analgesic purposes clinically.