Progress in Childhood Aplastic Anemia Treatment in 2004
From the Point of View of Hematopoietic Stem Cell Transplantation
2005 Volume 19 Issue 4 Pages 250-253
Details
2005 Volume 19 Issue 4 Pages 250-253
A total of 580 aplastic anemia (AA) related cases who received the first hematopoietic stem cell transplantation (SCT) between 1980 and 2002 were analyzed. Survival curves were calculated by overall survival (OS) and event free survival (EFS). They consisted of 494 AA, 53 Fanconi anemia, 30 pure red cell anemia (PRCA) and 3 other cases. They were 316 boys and 264 girls whose age at SCT ranged from 5 months (5 m) to 31 years 2 months (31y2m) (median 10y4m). The observation period ranged from 0 m to 250 m (median 69 m). OS/EFS of AA from HLA matched siblings, AA from other than HLA matched siblings, Fanconi anemia and PRCA were 85.0 ± 4.4%/76.5 ± 4.5%, 73.9±3.6%/68.9±3.8%, 48.0± 15.9%/48.0± 15.9% and 83.2±6.9%/73.2±8.1%, respectively.
