The Recovery of Peripheral Blood Cells after Allogeneic Bone Marrow Transplantation and Autologous Bone Marrow Transplantation

Abstract

We studied the recovery of in peripheral blood cells after allogeneic bone marrow transplantation (allo-BMT) and autologous bone marrow transplantation (auto-BMT). Twelve patients were studied, six allo-BMT and six auto-BMT. The basic diseases in the allo-BMT were ALL (4 cases), AML (1 case), and NHL (1 case) those in the auto-BMT were ALL (1 case), NHL (3 cases), and yolk sac tumor (2 cases). All twelve patients were treated with intensive chemotherapy and 12 Gy total body irradiation followed by BMT. As a result we found that the recovery of lymphocyte count in the auto-BMT was faster than in the allo-BMT. However, the recovery of neutrophil count and platelet count in the auto-BMT was slower than that of allo-BMT. Recovery of reticulocyte count and monocyte count did not show any significant difference between the two groups. Our results suggest that the standard methods of cryopreservation of bone marrow may be suboptimal.