Abstract
The Bone Marrow Transplantation Committee of the Society has conducted an annual registry of bone marrow transplantation in children in Japan since 1983. As of June 30, 1992, 1, 330 patients had received stem-cell transplantation and were registered from 74 institutions. Among them, autologous bone marrow transplantation and autologous peripheral blood stem-cell transplantation were mainly performed in hematological malignancies or malignant solid tumors, and the former procedure was done in 342 children (183 alive) and the latter one was done in 172 children (113 alive), respectively. Allogeneic or syngeneic bone marrow transplantation including fetal liver cell transplantation (5 cases) were given to 807 children, i.e. 222 cases of acute lymphocytic leukemia (117 alive), 206 cases of acute myeloid leukemia (133 alive), 57 cases of adult-type chronic-myelocytic leukemia (38 alive), 5 cases of juvenile-type chronic myelocytic leukemia (2 alive), 37 cases of non-Hodgkin lymphoma (29 alive), 23 cases of malignant solid tumors (14 alive), 154 cases of severe aplastic anemia (137 alive), 33 cases of severe combined immune deficiency (15 alive), and 62 other cases (46 alive). The total number of transplanted cases has increased from 1, 013 to 1, 330 during the past one year. The details are reported in this paper.