医療薬学
Online ISSN : 1882-1499
Print ISSN : 1346-342X
ISSN-L : 1346-342X
ノート
携帯型持続注入ポンプ内の薬液の混合性と安全な薬液充填法の検討
瀬名波 宏昌名徳 倫明廣谷 芳彦下村 一徳中西 晶子小角 麻衣土井 彩愛川口 進一高橋 幸一
著者情報
ジャーナル フリー

2013 年 39 巻 1 号 p. 39-44

詳細
抄録

It has been reported that 5-fluorouracil (5-FU) and saline were not mixed homogeneously in some portable infusion pumps when saline was loaded first and then 5-FU was added.We evaluated whether the homogeneity of the mixture can be improved by modifying the loading method. The ratio between a glucose solution instead of 5-FU and saline and the order of their loading were changed, and differences in the glucose concentration were evaluated by labeling with ethyl hydroxybenzoate. While characteristic unevenness of the concentration was noted when glucose solution was loaded after saline, as has been reported, the unevenness was reduced by mixing the contents by inverting the pump after loading regardless of the mixing ratio. Therefore, in loading drugs with high biological toxicity such as 5-FU, the homogeneity of the mixture is considered to be improved, and the safety of the procedure to be improved by reducing the risk of exposure if the drug is loaded after physiologic saline and mixed by inversion.

著者関連情報
© 2013 日本医療薬学会
前の記事 次の記事
feedback
Top