客観的データに基づいた点眼液の適正使用に関する検討

抄録

In recent years, the intervention of pharmacists in the proper use of eye drops in the elderly has led to improved adherence. It is also said to have been effective in preventing postoperative complications, preventing infections and avoiding adverse events. However, confirmation of eye drops adherence is subjective patient information. For this reason, it is often impossible to confirm the actual procedure, and it is not clear whether it was used correctly. Therefore, we conducted questionnaire surveys of patients undergoing cataract surgery to confirm the instillation status. In addition, we measured the weight of the ophthalmic solution after use and considered the relationship with the questionnaire. The subjects of the questionnaire were elderly people aged over 70 years old. The eye drops techniques were the upper and lower opening method (44.3％), the lower eyelid drooping method (42.3％), and others (13.4％). Subjects replied that they were generally properly instilled. As a result of measuring the solution weight, the actual value of the Moxifloxacin ophthalmic solution was significantly less than the appropriate value (P < 0.01). In addition, as a result of multivariate analysis, the factor that decreased the eye drops weight by more than 5％ was the patient who answered, “I can't apply well” (OR: 5.98, 95％CI: 1.31 - 35.29, P = 0.021). The subjective information of the elderly may be unreliable. Therefore, we need to conduct detailed interviews about the situation of instillation. In addition, training of techniques and periodic re-evaluation will lead to optimization and improvement of eye drops adherence.