薬局薬剤師による外来抗菌薬治療の適正化に関する疑義照会報告事例の解析

抄録

In the outpatient setting, pharmacists at community pharmacies play a crucial role by working closely with physicians to ensure appropriate antimicrobial use. This study aimed to clarify the actual condition of pharmaceutical inquiries by community pharmacists regarding the appropriate use of outpatient antibiotic therapy. Based on public data released by the Japan Council for Quality Health Care, we performed a retrospective analysis on 757 inquiries related to antibiotics among inquiries recorded by community pharmacists from March 2022 to July 2022. The most common inquiries were about the prevention of adverse effects of antibiotics (70.5％), followed by inquiries about the prevention of decrease in the effectiveness of antibiotics (10.0％). On the other hand, we found that pharmaceutical interventions to reduce unnecessary antibiotic prescriptions for the common cold and to promote the appropriate selection of antibiotics for empirical treatment through the implementation of clinical guidelines, and to optimize the dosage in cases of renal insufficiency estimated from the results of a creatinine test remained as important problems that still need to be solved. In conclusion, our findings suggest that although community pharmacists’ inquiries contribute substantially to the safety and treatment effectiveness of outpatient antibiotic therapy, pharmacists may need to better identify problems before their onset in order to promote the appropriate use of antibiotics.